Sept. 22

I. Exponential growth vs. logarithmic growth
a. bacteria don't grow exponentailly forever (or else the whole lab would be filled with the bacteria we grew during our test right now)
b. bacteria have logarithmic growth
II. How an individual bacterium divides
a. Replication of chromosome
1. Chromosome is circular-> no clear "beginning" site for replication
2. OriC:sequence of DNA on bacterial chromosome where replication starts
3. DNA must be unwound to be copied
4. topoisomerase IV de-links copied chromosomes
5. Bacterial DNA then copied in a semiconservative fasshion-one strand new, other a copy
6. Mutation: change in DNA sequence of organism (compared to original)-MEMORIZE!!!!!
i.most often occur during cell division
b. Elongation of cell
1. Done by makin new cell envelope stuff n middle (stuff depends on bacteria type)
c. Formation of FtsZ ring at septum
1. septum: division between 2 bacteria
2. FtsZ similar to a protein in eukaryotes but still with major differences
d. Building of new cell envelope components at septum

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