Nov. 3 notes

Mismatch repair system
similar systems in bacteria, eukaryotes
how it works:
1) find mismatched bases
2) unmethylated strand= one with error (because it is newer)
3) endonuclease= enzyme, cut just one strand of double stranded DNA, eats swatch of single stranded DNA
Then, DNA polymerase (which brings more bases) synthesizes new swatch, then DNA ligase patches together fragments

V.a. methylation of DNA -advantage:be able to tell own DNA from foreign DNA (by which we mean, own cells DNA vs. Viral DNA)
b. restriction enzymes: cut DNA into fragments at specific sequences (linear DNA especially affected by restriction enzymes)

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